Mnogi imaju problema sa skidanjem sa benzodiazepini(xanax, rivotril, diazepam itd) i godinama imaju simptome ustezanja i poremečen skroz glutamat/gabu.
Još par zanimljivih studija za neurodegenerativne bolesti i remijelinaciju(ms).
Quote:
This is study that was interesting when I was researching it:
https://e-bnr.org/DOIx.php?id=10.12786/bn.2019.12.e2
CONCLUSION
Agmatine has been found to have neuroprotective effect in both acute and chronic CNS disorders. Agmatine modulates different receptors and ion channels that are responsible for the progression and resolution of CNS injury. There are a number of studies that reported that, both endogenous and exogenous agmatine possess beneficiary role on most CNS cells such as neuron, astrocytes, microglia and oligodendrocytes and also modulate the differentiation, proliferation and migration of those cells. Therefore, it is important to understand the mechanism of agmatine action on CNS cells which will help to understand the therapeutic potential of agmatine in CNS injury.
Agmatine treatment promoted remyelination
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549976/
What it does is antagonize NMDA receptors(pro glutamate receptors that damage brain) and increase circulation where it needs(peripheral or brain circulation).it is one of the easiest molecules that pass blood brain barrier.
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Prije 3g uz agmatin i NAC skinuo sam se sa pregabalin cold turkey(živa istina) bez posljedica ikakvih šta je nezapamćeno.
Agmatin ima drugačiji arginase transport od arginina i citrulina i ne izaziva herpes.
Mnogi prijavljuju benefite za long covid, neuropatiju tankih vlakana i fibromijalgiju.
Ovo je studija dugoročnog uzimanja:
https://pubmed.ncbi.nlm.nih.gov/25247837/